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Sunday, March 23, 2008

Medical options

Some people with type 2 diabetes are treated with insulin. Though some insulin is available over the counter, people should obtain an accurate diagnosis, as well as thorough guidance from their healthcare provider, before self-medicating. Insulin preparations are grouped according to onset and duration of action either as rapid-acting, such as regular (Humulin R, Novolin R); intermediate-acting, such as NPH (Humulin N, Novolin N) and lente (Humulin L, Novolin L); and long-acting, such as ultralente (Humulin U). Oral glucose tablets (such as B-D Glucose) and gels (Glutose, Insta-Glucose, and Insulin Reaction) are available to treat low blood sugar resulting from insulin overdose.

Prescription-only insulin includes insulin analog injection (Humalog, Novolog), insulin injection concentrated (Humulin R Regular U-500), insulin detemir injection (Levemir), insulin glargine (Lantus), insulin glulisine (Apidra), and human insulin powder for inhalation (Exubera). Injectable glucagon (Glucagon Emergency Kit) is used to treat severe hypoglycemia resulting from insulin overdose.

Common prescription medications used specifically to treat type 2 diabetes include sulfonylureas, such as glipizide (Glucotrol, Glucotrol XL), glimepiride (Amaryl), and glyburide (DiaBeta, Micronase, Glynase PresTab); the biguanide metformin (Glucophage); the meglitinides repaglinide (Prandin) and nateglinide (Starlix); alpha-glucosidase inhibitors including acarbose (Precose), and miglitol (Glyset); the incretin mimetic agent exenatide (Byetta); and thiazolidinediones, such as rosiglitazone (Avandia) and pioglitazone (Actos). Many oral antidiabetic drugs are also available in combination products. Injectable glucagon (Glucagon Emergency Kit) is used to treat severe hypoglycemia resulting from insulin overdose.

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